Structure of a Spliceosome: Molecular Framework for Understanding Pre-mRNA Splicing – Beauty of Science
One Gene-One Peptide Hypothesis was a bold statement proposed by Edward Tatum and George Beadle in 1941 heralding the nascent field of molecular genetics. The proposal was long before we knew anything about the nature and structure of the DNA. It was rather vague how a gene encoded a protein. The Central Dogma of biology was coined by Francis Crick in late 1950s but the intermediate molecule known as the messenger RNA was identified (?) in 1960 by Arthur Pardee, […]
















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